› 2cr3

Solution NMR

Solution structure of the first Ig-like domain of human fibroblast growth factor receptor 1

Released:
DOI: 10.2210/pdb2cr3/pdb
PDB entry 2cr3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2cr3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2cr3 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Hatta R, Hayashi F, Yoshida M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145801 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 10.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P11362 (Residues: 38-123; Coverage: 11%)
Gene names: BFGFR, CEK, FGFBR, FGFR1, FLG, FLT2, HBGFR
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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