› 2d3j

Solution NMR

NMR structure of the WIF domain from human WIF-1

Released:
DOI: 10.2210/pdb2d3j/pdb
PDB entry 2d3j coloured by chain, ensemble of 20 models, front view.
PDB entry 2d3j coloured by chain, ensemble of 20 models, side view.
PDB entry 2d3j coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure of the WIF domain of the human Wnt-inhibitory factor-1.
Liepinsh E, Bányai L, Patthy L, Otting G
J Mol Biol 357 942-50 (2006)
PMID: 16476441

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195288 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Wnt inhibitory factor 1 Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 17.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y5W5 (Residues: 32-181; Coverage: 43%)
Gene names: UNQ191/PRO217, WIF1
Sequence domains: WIF domain
Structure domains: Wnt, WIF domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 review citations

Wnt proteins.
Willert et al. (2012)
9 more

2 mentions without citation

The structural biology of canonical Wnt signalling.
Agostino et al. (2020)
1 more