2di0

Solution NMR

Solution Structure of the CUE Domain in the Human Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2)

Released:
Source organism: Homo sapiens
Entry authors: Zhao C, Kigawa T, Tochio N, Koshiba S, Harada T, Watanabe S, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-190515 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Activating signal cointegrator 1 complex subunit 2 Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 7.89 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: Q9H1I8 (Residues: 463-525; Coverage: 8%)
Gene names: ASC1P100, ASCC2, RQT3
Sequence domains: CUE domain
Structure domains: DNA helicase RuvA subunit, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Cell free synthesis