› 2dig

Solution NMR

Solusion structure of the Todor domain of human Lamin-B receptor

Released:
DOI: 10.2210/pdb2dig/pdb
PDB entry 2dig coloured by chain, ensemble of 20 models, front view.
PDB entry 2dig coloured by chain, ensemble of 20 models, side view.
PDB entry 2dig coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Yoneyama M, Tochio N, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP(+) = 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol + NADPH
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172092 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Delta(14)-sterol reductase LBR Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.37 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: Q14739 (Residues: 1-55; Coverage: 9%)
Gene name: LBR
Sequence domains: Lamin-B receptor of TUDOR domain
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Cell free synthesis

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