› 2diz

Solution NMR

The solution structure of the third thioredoxin domain of human Thioredoxin domain-containing protein 5

Released:
DOI: 10.2210/pdb2diz/pdb
PDB entry 2diz coloured by chain, ensemble of 20 models, front view.
PDB entry 2diz coloured by chain, ensemble of 20 models, side view.
PDB entry 2diz coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Tochio N, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Catalyzes the rearrangement of -S-S- bonds in proteins
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185480 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein 5 Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 12.79 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: Q8NBS9 (Residues: 323-432; Coverage: 28%)
Gene names: TLP46, TXNDC5, UNQ364/PRO700
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Cell free synthesis

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