› 2dl2

X-ray diffraction
3Å resolution

KILLER IMMUNOGLOBULIN RECEPTOR 2DL2

Released:
DOI: 10.2210/pdb2dl2/pdb
PDB entry 2dl2 coloured by chain, front view.
PDB entry 2dl2 coloured by chain, side view.
PDB entry 2dl2 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2.
Snyder GA, Brooks AG, Sun PD
Proc Natl Acad Sci U S A 96 3864-9 (1999)
PMID: 10097129

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155112 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Killer cell immunoglobulin-like receptor 2DL2 Chain: A
Molecule details ›
Chain: A
Length: 197 amino acids
Theoretical weight: 21.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P43627 (Residues: 25-221; Coverage: 60%)
Gene names: CD158B1, KIR2DL2, NKAT6
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P212121
Unit cell:
a: 40.5Å b: 71.5Å c: 88.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.219 0.309
Expression system: Escherichia coli BL21

Quick links

Citations

24 review citations

KIR: diverse, rapidly evolving receptors of innate and adaptive immunity.
Vilches et al. (2002)
23 more

27 mentions without citation

The Yin and Yang of HLA and KIR in human disease.
Kulkarni et al. (2008)
26 more