› 2dlw

Solution NMR

Solution structure of the IRS domain of human docking protein 2, isoform a

Released:
DOI: 10.2210/pdb2dlw/pdb
PDB entry 2dlw coloured by chain, ensemble of 20 models, front view.
PDB entry 2dlw coloured by chain, ensemble of 20 models, side view.
PDB entry 2dlw coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Zhang HP, Kurosaki C, Yoshida M, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Docking protein 2 Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.5 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: O60496 (Residues: 148-247; Coverage: 24%)
Gene name: DOK2
Sequence domains: PTB domain (IRS-1 type)
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Cell free synthesis

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