› 2do3

Solution NMR

Solution structure of the third KOW motif of transcription elongation factor SPT5

Released:
DOI: 10.2210/pdb2do3/pdb
PDB entry 2do3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2do3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2do3 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Tanabe W, Suzuki S, Muto Y, Inoue M, Kigawa T, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126211 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription elongation factor SPT5 Chain: A
Molecule details ›
Chain: A
Length: 69 amino acids
Theoretical weight: 7.74 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: O00267 (Residues: 462-523; Coverage: 6%)
Gene names: SPT5, SPT5H, SUPT5H
Sequence domains: KOW motif
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dyanamics, simulated annealing
Expression system: Cell free synthesis

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