2eax

X-ray diffraction
2.1Å resolution

Crystal structure of human PGRP-IBETAC in complex with glycosamyl muramyl pentapeptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-162678 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Peptidoglycan recognition protein 4 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 164 amino acids
Theoretical weight: 17.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96LB8 (Residues: 210-373; Coverage: 46%)
Gene names: PGLYRP4, PGRPIB, SBBI67
Sequence domains: N-acetylmuramoyl-L-alanine amidase
Structure domains: Peptidoglycan recognition protein-like
GLYCOSAMYL MURAMYL PENTAPEPTIDE Chain: L
Molecule details ›
Chain: L
Length: 5 amino acids
Theoretical weight: 490 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

Carbohydrate polymer : NEW Components: AMV, NAG
No bound ligands
2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 41.94Å b: 61.39Å c: 97.95Å
α: 90° β: 96.45° γ: 90°
R-values:
R R work R free
0.218 0.21 0.242
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided