› 2ej4

Solution NMR

Functional and structural basis of nuclear localization signal in ZIC3 zinc finger domain: a role of conserved tryptophan residue in the zinc finger domain

Released:
DOI: 10.2210/pdb2ej4/pdb
PDB entry 2ej4 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ej4 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ej4 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Tomizawa T, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129986 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger protein ZIC 3 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.63 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O60481 (Residues: 245-326; Coverage: 18%)
Gene names: ZIC3, ZNF203
Sequence domains: Zic proteins zinc finger domain
Structure domains: Classic Zinc Finger

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Not provided

Quick links