› 2ejs

Solution NMR

Solution structure of RUH-076, a human CUE domain

Released:
DOI: 10.2210/pdb2ejs/pdb
PDB entry 2ejs coloured by chain, ensemble of 20 models, front view.
PDB entry 2ejs coloured by chain, ensemble of 20 models, side view.
PDB entry 2ejs coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Ruhul Momen AZM, Kitasaka S, Hirota H, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-S-ubiquitinyl-L-cysteine
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193863 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 ubiquitin-protein ligase AMFR Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.36 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9UKV5 (Residues: 452-502; Coverage: 8%)
Gene names: AMFR, RNF45
Sequence domains: CUE domain
Structure domains: DNA helicase RuvA subunit, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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