› 2elb

X-ray diffraction
2.6Å resolution

Crystal Structure of the BAR-PH domain of human APPL1

Released:
DOI: 10.2210/pdb2elb/pdb
PDB entry 2elb coloured by chain, front view.
PDB entry 2elb coloured by chain, side view.
PDB entry 2elb coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of the BAR-PH and PTB domains of human APPL1.
Li J, Mao X, Dong LQ, Liu F, Tong L
Structure 15 525-33 (2007)
PMID: 17502098

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193847 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DCC-interacting protein 13-alpha Chain: A
Molecule details ›
Chain: A
Length: 396 amino acids
Theoretical weight: 45.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UKG1 (Residues: 1-376; Coverage: 53%)
Gene names: APPL, APPL1, DIP13A, KIAA1428
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P21212
Unit cell:
a: 100.568Å b: 104.126Å c: 37.074Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.236 0.327
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

11 review citations

Mechanisms shaping the membranes of cellular organelles.
Shibata et al. (2009)
10 more

4 mentions without citation

SnapShot: membrane curvature sensors and generators.
Shen et al. (2012)
3 more