› 2ezy

Solution NMR

SOLUTION STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR BAF, NMR, ENSEMBLE OF 20 SIMULATED ANNEALING STRUCTURES

Released:
DOI: 10.2210/pdb2ezy/pdb
PDB entry 2ezy coloured by chain, ensemble of 20 models, front view.
PDB entry 2ezy coloured by chain, ensemble of 20 models, side view.
PDB entry 2ezy coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the cellular factor BAF responsible for protecting retroviral DNA from autointegration.
Cai M, Huang Y, Zheng R, Wei SQ, Ghirlando R, Lee MS, Craigie R, Gronenborn AM, Clore GM
Nat Struct Biol 5 903-9 (1998)
PMID: 9783751

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131036 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Barrier-to-autointegration factor Chains: A, B
Molecule details ›
Chains: A, B
Length: 89 amino acids
Theoretical weight: 10.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75531 (Residues: 1-89; Coverage: 100%)
Gene names: BAF, BANF1, BCRG1
Sequence domains: Barrier to autointegration factor
Structure domains: Barrier-to-autointegration factor, BAF

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

10 review citations

The nuclear envelope, muscular dystrophy and gene expression.
Wilson KL. (2000)
9 more

1 mention without citation

Common fold in helix-hairpin-helix proteins.
Shao et al. (2000)