› 2fnb

Solution NMR

NMR STRUCTURE OF THE FIBRONECTIN ED-B DOMAIN, NMR, 20 STRUCTURES

Released:
DOI: 10.2210/pdb2fnb/pdb
PDB entry 2fnb coloured by chain, ensemble of 20 models, front view.
PDB entry 2fnb coloured by chain, ensemble of 20 models, side view.
PDB entry 2fnb coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure of the human oncofoetal fibronectin ED-B domain, a specific marker for angiogenesis.
Fattorusso R, Pellecchia M, Viti F, Neri P, Neri D, Wüthrich K
Structure 7 381-90 (1999)
PMID: 10196121

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136132 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ugl-Y3 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02751 (Residues: 1262-1356; Coverage: 4%)
Gene names: FN, FN1
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Tumour vascular targeting.
Neri et al. (2005)
3 more

5 mentions without citation

Structural insights into fibronectin type III domain-mediated signaling.
Bencharit et al. (2007)
4 more