› 2fv8

X-ray diffraction
1.9Å resolution

The crystal structure of RhoB in the GDP-bound state

Released:
DOI: 10.2210/pdb2fv8/pdb
PDB entry 2fv8 coloured by chain, front view.
PDB entry 2fv8 coloured by chain, side view.
PDB entry 2fv8 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Turnbull AP, Soundararajan M, Smee C, Johansson C, Schoch G, Gorrec F, Bray J, Papagrigoriou E, von Delft F, Weigelt J, Edwards A, Arrowsmith C, Sundstrom M, Doyle D, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158666 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho-related GTP-binding protein RhoB Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 23.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62745 (Residues: 4-187; Coverage: 94%)
Gene names: ARH6, ARHB, RHOB
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2
Unit cell:
a: 137.519Å b: 42.233Å c: 33.85Å
α: 90° β: 90.58° γ: 90°
R-values:
R R work R free
0.212 0.21 0.253
Expression system: Escherichia coli

Quick links