› 2g0n

X-ray diffraction
1.9Å resolution

The Crystal Structure of the Human RAC3 in complex with GDP and Chloride

Released:
DOI: 10.2210/pdb2g0n/pdb
PDB entry 2g0n coloured by chain, front view.
PDB entry 2g0n coloured by chain, side view.
PDB entry 2g0n coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ugochukwu E, Yang X, Zao Y, Elkins J, Gileadi C, Burgess N, Colebrook S, Gileadi O, Fedorov O, Bunkoczi G, Sundstrom M, Arrowsmith C, Weigelt J, Edwards A, von Delft F, Doyle D, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158088 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related C3 botulinum toxin substrate 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 179 amino acids
Theoretical weight: 19.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P60763 (Residues: 1-177; Coverage: 92%)
Gene name: RAC3
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
Ligand MG 2 x MG
Ligand CL 3 x CL
Ligand GDP 2 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P212121
Unit cell:
a: 53.932Å b: 80.841Å c: 84.563Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.165 0.221
Expression system: Escherichia coli

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