› 2g1l

X-ray diffraction
2.6Å resolution

Crystal structure of the FHA domain of human kinesin family member C

Released:
DOI: 10.2210/pdb2g1l/pdb
PDB entry 2g1l coloured by chain, front view.
PDB entry 2g1l coloured by chain, side view.
PDB entry 2g1l coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang J, Tempel W, Shen Y, Shen L, Arrowsmith C, Edwards A, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-129155 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF1C Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 11.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43896 (Residues: 498-599; Coverage: 9%)
Gene names: KIAA0706, KIF1C
Sequence domains: FHA domain
Structure domains: Tumour Suppressor Smad4

Ligands and Environments

3 bound ligands:
Ligand CL 1 x CL
Ligand NI 1 x NI
Ligand UNX 1 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P6122
Unit cell:
a: 107.62Å b: 107.62Å c: 82.995Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.215 0.243
Expression system: Escherichia coli

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