› 2gee

X-ray diffraction
2.01Å resolution

Crystal Structure of Human Type III Fibronectin Extradomain B and Domain 8

Released:
DOI: 10.2210/pdb2gee/pdb
PDB entry 2gee coloured by chain, front view.
PDB entry 2gee coloured by chain, side view.
PDB entry 2gee coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into fibronectin type III domain-mediated signaling.
Bencharit S, Cui CB, Siddiqui A, Howard-Williams EL, Sondek J, Zuobi-Hasona K, Aukhil I
J Mol Biol 367 303-9 (2007)
PMID: 17261313

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136132 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ugl-Y3 Chain: A
Molecule details ›
Chain: A
Length: 203 amino acids
Theoretical weight: 22.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02751 (Residues: 1266-1447; Coverage: 7%)
Gene names: FN, FN1
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 43.407Å b: 55.288Å c: 74.903Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.249 0.301
Expression system: Escherichia coli

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Citations

6 review citations

Genetics of congenital hypogonadotropic hypogonadism: peculiarities and phenotype of an oligogenic disease.
Cangiano et al. (2021)
5 more

4 mentions without citation

Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Barr et al. (2009)
3 more