› 2gl8

X-ray diffraction
2.4Å resolution

Human Retinoic acid receptor RXR-gamma ligand-binding domain

Released:
DOI: 10.2210/pdb2gl8/pdb
PDB entry 2gl8 coloured by chain, front view.
PDB entry 2gl8 coloured by chain, side view.
PDB entry 2gl8 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Min JR, Schuetz A, Loppnau P, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Plotnikov AN, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155733 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinoic acid receptor RXR-gamma Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 241 amino acids
Theoretical weight: 27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P48443 (Residues: 227-463; Coverage: 51%)
Gene names: NR2B3, RXRG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 48.07Å b: 161.316Å c: 68.682Å
α: 90° β: 109.5° γ: 90°
R-values:
R R work R free
0.245 0.243 0.296
Expression system: Escherichia coli

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