› 2gmd

Solution NMR

Structure of C12-LF11 bound to the SDS micelles

Released:
DOI: 10.2210/pdb2gmd/pdb
PDB entry 2gmd coloured by chain, ensemble of 20 models, front view.
PDB entry 2gmd coloured by chain, ensemble of 20 models, side view.
PDB entry 2gmd coloured by chain, ensemble of 20 models, top view.
Source organism: synthetic construct
Primary publication:
The acyl group as the central element of the structural organization of antimicrobial lipopeptide.
Japelj B, Zorko M, Majerle A, Pristovsek P, Sanchez-Gomez S, Martinez de Tejada G, Moriyon I, Blondelle SE, Brandenburg K, Andrä J, Lohner K, Jerala R
J Am Chem Soc 129 1022-3 (2007)
PMID: 17263370

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136228 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactoferricin-H Chain: A
Molecule details ›
Chain: A
Length: 12 amino acids
Theoretical weight: 1.53 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P02788 (Residues: 39-49; Coverage: 2%)
Gene names: GIG12, LF, LTF

Ligands and Environments

1 bound ligand:
Ligand DAO 1 x DAO
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

4 review citations

Antimicrobial peptides for therapeutic applications: a review.
Seo et al. (2012)
3 more