2gys

X-ray diffraction
2.7Å resolution

2.7 A structure of the extracellular domains of the human beta common receptor involved in IL-3, IL-5, and GM-CSF signalling

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-152514 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Cytokine receptor common subunit beta Chains: A, B
Molecule details ›
Chains: A, B
Length: 419 amino acids
Theoretical weight: 47.81 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P32927 (Residues: 25-285, 286-437; Coverage: 47%)
Gene names: CSF2RB, IL3RB, IL5RB
Sequence domains: GM-CSF/IL-3/IL-5 receptor common beta subunit, N-terminal
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, FUC
Carbohydrate polymer : NEW Components: NAG, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-ID-B
Spacegroup: R3
Unit cell:
a: 184.909Å b: 184.909Å c: 101.047Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.214 0.212 0.269
Expression system: Trichoplusia ni