2h24

X-ray diffraction
2Å resolution

Crystal structure of human IL-10

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149579 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-10 Chain: A
Molecule details ›
Chain: A
Length: 160 amino acids
Theoretical weight: 18.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P22301 (Residues: 19-178; Coverage: 100%)
Gene name: IL10
Sequence domains: Interleukin 10
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P43212
Unit cell:
a: 36.37Å b: 36.37Å c: 220.97Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.254
Expression system: Escherichia coli