› 2h45

Solution NMR

Solution structure of the second type III domain of human Fibronectin: ensemble of 25 structures

Released:
DOI: 10.2210/pdb2h45/pdb
PDB entry 2h45 coloured by chain, ensemble of 25 models, front view.
PDB entry 2h45 coloured by chain, ensemble of 25 models, side view.
PDB entry 2h45 coloured by chain, ensemble of 25 models, top view.
Source organism: Homo sapiens
Primary publication:
Interdomain association in fibronectin: insight into cryptic sites and fibrillogenesis.
Vakonakis I, Staunton D, Rooney LM, Campbell ID
EMBO J 26 2575-83 (2007)
PMID: 17464288

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136132 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ugl-Y3 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02751 (Residues: 721-809; Coverage: 4%)
Gene names: FN, FN1
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: Simulated annealing in cartesian space
Expression system: Escherichia coli

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Citations

12 review citations

Assembly of fibronectin extracellular matrix.
Singh et al. (2010)
11 more

4 mentions without citation

Interdomain association in fibronectin: insight into cryptic sites and fibrillogenesis.
Vakonakis et al. (2007)
3 more