Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140725 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transportin-1
Molecule details ›
Chains: A, B
Length: 865 amino acids
Theoretical weight: 98.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 865 amino acids
Theoretical weight: 98.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q92973 (Residues: 9-343, 376-898; Coverage: 96%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
Molecule details ›
Chains: C, D
Length: 49 amino acids
Theoretical weight: 5.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Heterogeneous nuclear ribonucleoprotein A1, LC domain
Length: 49 amino acids
Theoretical weight: 5.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P09651 (Residues: 309-357; Coverage: 13%)
Sequence domains: Heterogeneous nuclear ribonucleoprotein A1, LC domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
C2
Expression system: Escherichia coli BL21
