› 2ha1

Solution NMR

Complex of the first and second type III domains of human Fibronectin in solution

Released:
DOI: 10.2210/pdb2ha1/pdb
PDB entry 2ha1 coloured by chain, ensemble of 39 models, front view.
PDB entry 2ha1 coloured by chain, ensemble of 39 models, side view.
PDB entry 2ha1 coloured by chain, ensemble of 39 models, top view.
Source organism: Homo sapiens
Primary publication:
Interdomain association in fibronectin: insight into cryptic sites and fibrillogenesis.
Vakonakis I, Staunton D, Rooney LM, Campbell ID
EMBO J 26 2575-83 (2007)
PMID: 17464288

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136132 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ugl-Y1 Chain: A
Molecule details ›
Chain: A
Length: 201 amino acids
Theoretical weight: 22.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02751 (Residues: 609-809; Coverage: 8%)
Gene names: FN, FN1
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Rigid body docking with torsional flexibility at the interfacial amino acid sidechains
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Assembly of fibronectin extracellular matrix.
Singh et al. (2010)
11 more

7 mentions without citation

Protein unfolding under isometric tension-what force can integrins generate, and can it unfold FNIII domains?
Erickson HP. (2017)
6 more