› 2hf6

Solution NMR

Solution structure of human zeta-COP

Released:
DOI: 10.2210/pdb2hf6/pdb
PDB entry 2hf6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2hf6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2hf6 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats.
Yu W, Lin J, Jin C, Xia B
J Mol Biol 386 903-12 (2009)
PMID: 19167404

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158434 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coatomer subunit zeta-1 Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 17.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61923 (Residues: 1-149; Coverage: 84%)
Gene names: CGI-120, COPZ, COPZ1, HSPC181
Sequence domains: Clathrin adaptor complex small chain
Structure domains: Beta-Lactamase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The COPI system: molecular mechanisms and function.
Beck et al. (2009)
4 more

5 mentions without citation

Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy.
Cui et al. (2022)
4 more