› 2hft

X-ray diffraction
1.69Å resolution

THE CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR AT 1.7 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb2hft/pdb
PDB entry 2hft coloured by chain, front view.
PDB entry 2hft coloured by chain, side view.
PDB entry 2hft coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The crystal structure of the extracellular domain of human tissue factor refined to 1.7 A resolution.
Muller YA, Ultsch MH, de Vos AM
J Mol Biol 256 144-59 (1996)
PMID: 8609606

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146733 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tissue factor Chain: A
Molecule details ›
Chain: A
Length: 218 amino acids
Theoretical weight: 24.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13726 (Residues: 33-194, 195-243; Coverage: 80%)
Gene name: F3
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P41212
Unit cell:
a: 45.2Å b: 45.2Å c: 230.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 not available 0.254
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Interleukin-10 and related cytokines and receptors.
Pestka et al. (2004)
11 more

13 mentions without citation

Tissue factor controversies.
Mann et al. (2012)
12 more