› 2hgn

Solution NMR

NMR structure of the third qRRM domain of human hnRNP F

Released:
DOI: 10.2210/pdb2hgn/pdb
PDB entry 2hgn coloured by chain, ensemble of 15 models, front view.
PDB entry 2hgn coloured by chain, ensemble of 15 models, side view.
PDB entry 2hgn coloured by chain, ensemble of 15 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure of the three quasi RNA recognition motifs (qRRMs) of human hnRNP F and interaction studies with Bcl-x G-tract RNA: a novel mode of RNA recognition.
Dominguez C, Allain FH
Nucleic Acids Res 34 3634-45 (2006)
PMID: 16885237

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156579 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heterogeneous nuclear ribonucleoprotein F, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P52597 (Residues: 277-381; Coverage: 25%)
Gene names: HNRNPF, HNRPF
Sequence domains:
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

12 review citations

RNA-binding proteins: modular design for efficient function.
Lunde et al. (2007)
11 more

2 mentions without citation

NMR structure of the three quasi RNA recognition motifs (qRRMs) of human hnRNP F and interaction studies with Bcl-x G-tract RNA: a novel mode of RNA recognition.
Dominguez et al. (2006)
1 more