› 2hqe

X-ray diffraction
2Å resolution

Crystal structure of human P100 Tudor domain: Large fragment

Released:
DOI: 10.2210/pdb2hqe/pdb
PDB entry 2hqe coloured by chain, front view.
PDB entry 2hqe coloured by chain, side view.
PDB entry 2hqe coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Shah N, Zhao M, Cheng C, Xu H, Yang J, Silvennoinen O, Liu ZJ, Wang BC, Southeast Collaboratory for Structural Genomics (SECSG)

Function and Biology Details

Reaction catalysed: 
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181617 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Staphylococcal nuclease domain-containing protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 246 amino acids
Theoretical weight: 27.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q7KZF4 (Residues: 665-910; Coverage: 27%)
Gene names: SND1, TDRD11
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 49.931Å b: 93.413Å c: 95.279Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.233 0.249
Expression system: Escherichia coli BL21

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