› 2htg

Solution NMR

Structural and functional characterization of TM VII of the NHE1 isoform of the Na+/H+ exchanger

Released:
DOI: 10.2210/pdb2htg/pdb
PDB entry 2htg coloured by chain, ensemble of 66 models, front view.
PDB entry 2htg coloured by chain, ensemble of 66 models, side view.
PDB entry 2htg coloured by chain, ensemble of 66 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional characterization of transmembrane segment VII of the Na+/H+ exchanger isoform 1.
Ding J, Rainey JK, Xu C, Sykes BD, Fliegel L
J Biol Chem 281 29817-29 (2006)
PMID: 16861220

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126698 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation/H+ exchanger domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 28 amino acids
Theoretical weight: 3.08 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O08938 (Residues: 36-60; Coverage: 16%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing; torsion angle dynamics
Expression system: Not provided

Quick links

Citations

9 review citations

Structural and functional analysis of the Na+/H+ exchanger.
Slepkov et al. (2007)
8 more