› 2hvz

Solution NMR

Solution structure of the RRM domain of SR rich factor 9G8

Released:
DOI: 10.2210/pdb2hvz/pdb
PDB entry 2hvz coloured by chain, ensemble of 20 models, front view.
PDB entry 2hvz coloured by chain, ensemble of 20 models, side view.
PDB entry 2hvz coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8.
Hargous Y, Hautbergue GM, Tintaru AM, Skrisovska L, Golovanov AP, Stevenin J, Lian LY, Wilson SA, Allain FH
EMBO J 25 5126-37 (2006)
PMID: 17036044

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172533 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/arginine-rich splicing factor 7 Chain: A
Molecule details ›
Chain: A
Length: 101 amino acids
Theoretical weight: 11.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16629 (Residues: 11-98; Coverage: 37%)
Gene names: SFRS7, SRSF7
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

20 review citations

RNA-binding proteins: modular design for efficient function.
Lunde et al. (2007)
19 more

3 mentions without citation

Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8.
Hargous et al. (2006)
2 more