› 2hy8

X-ray diffraction
2Å resolution

PAK1 complex with ST2001

Released:
DOI: 10.2210/pdb2hy8/pdb
PDB entry 2hy8 coloured by chain, front view.
PDB entry 2hy8 coloured by chain, side view.
PDB entry 2hy8 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Schulze-Gahmen U, Lu H

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171568 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase PAK 1 Chain: 1
Molecule details ›
Chain: 1
Length: 297 amino acids
Theoretical weight: 33.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13153 (Residues: 249-545; Coverage: 55%)
Gene name: PAK1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand 1ST 1 x 1ST
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: C2221
Unit cell:
a: 50.865Å b: 103.828Å c: 123.193Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.208 0.234
Expression system: Escherichia coli

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