2hyu

X-ray diffraction
1.86Å resolution

Human Annexin A2 with heparin tetrasaccharide bound

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139552 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Annexin A2 Chain: A
Molecule details ›
Chain: A
Length: 308 amino acids
Theoretical weight: 35.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07355 (Residues: 32-339; Coverage: 91%)
Gene names: ANX2, ANX2L4, ANXA2, CAL1H, LPC2D
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

Carbohydrate polymer : NEW Components: SGN, IDS, UAP
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P21212
Unit cell:
a: 107.934Å b: 54.301Å c: 68.896Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.233
Expression system: Escherichia coli BL21(DE3)