› 2i08

X-ray diffraction
2Å resolution

Solvation effect in conformational changes of EF-hand proteins: X-ray structure of Ca2+-saturated double mutant Q41L-K75I of N-domain of calmodulin

Released:
DOI: 10.2210/pdb2i08/pdb
PDB entry 2i08 coloured by chain, front view.
PDB entry 2i08 coloured by chain, side view.
PDB entry 2i08 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ababou A, Parkinson GN, Desjarlais JR, Djordjevic S

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143908 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 78 amino acids
Theoretical weight: 8.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P0DP23 (Residues: 2-79; Coverage: 52%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3221
Unit cell:
a: 38.4Å b: 38.4Å c: 81.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.24 0.239 0.243
Expression system: Escherichia coli BL21

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