› 2i7a

X-ray diffraction
1.8Å resolution

Domain IV of Human Calpain 13

Released:
DOI: 10.2210/pdb2i7a/pdb
PDB entry 2i7a coloured by chain, front view.
PDB entry 2i7a coloured by chain, side view.
PDB entry 2i7a coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Walker JR, Ng K, Davis TL, Ravulapalli R, Butler-cole C, Finerty Jr PJ, Newman EM, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179922 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calpain-13 Chain: A
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 19.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6MZZ7 (Residues: 515-669; Coverage: 23%)
Gene name: CAPN13
Structure domains: EF-hand

Ligands and Environments

3 bound ligands:
Ligand CA 1 x CA
Ligand SO4 4 x SO4
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P3221
Unit cell:
a: 86.115Å b: 86.115Å c: 47.417Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.171 0.169 0.197
Expression system: Escherichia coli BL21(DE3)

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