› 2i7k

Solution NMR

Solution Structure of the Bromodomain of Human BRD7 Protein

Released:
DOI: 10.2210/pdb2i7k/pdb
PDB entry 2i7k coloured by chain, ensemble of 20 models, front view.
PDB entry 2i7k coloured by chain, ensemble of 20 models, side view.
PDB entry 2i7k coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4.
Sun H, Liu J, Zhang J, Shen W, Huang H, Xu C, Dai H, Wu J, Shi Y
Biochem Biophys Res Commun 358 435-41 (2007)
PMID: 17498659

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192484 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain-containing protein 7 Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NPI1 (Residues: 129-236; Coverage: 17%)
Gene names: BP75, BRD7, CELTIX1
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

Histones: annotating chromatin.
Campos et al. (2009)
11 more

4 mentions without citation

Polybromo-1: the chromatin targeting subunit of the PBAF complex.
Thompson M. (2009)
3 more