Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Vinculin and Invasin IpaA (preferred)
PDBe Complex ID:
PDB-CPX-148245 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vinculin
Molecule details ›
Chain: A
Length: 266 amino acids
Theoretical weight: 30.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Vinculin family
Structure domains: Alpha-catenin/vinculin-like
Length: 266 amino acids
Theoretical weight: 30.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P18206 (Residues: 1-258; Coverage: 23%)
Sequence domains: Vinculin family
Structure domains: Alpha-catenin/vinculin-like
Invasin IpaA
Molecule details ›
Chains: B, D
Length: 25 amino acids
Theoretical weight: 2.75 KDa
Source organism: Shigella flexneri
Expression system: Escherichia coli
UniProt:
Sequence domains: SipA vinculin binding site
Length: 25 amino acids
Theoretical weight: 2.75 KDa
Source organism: Shigella flexneri
Expression system: Escherichia coli
UniProt:
- Canonical: P18010 (Residues: 563-587; Coverage: 4%)
Sequence domains: SipA vinculin binding site
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
P4332
Expression system: Escherichia coli
