2il6

Solution NMR

HUMAN INTERLEUKIN-6, NMR, 32 STRUCTURES

Released:
Source organism: Homo sapiens
Primary publication:
Solution structure of recombinant human interleukin-6.
J Mol Biol 268 468-81 (1997)
PMID: 9159484

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138614 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-6 Chain: A
Molecule details ›
Chain: A
Length: 185 amino acids
Theoretical weight: 21.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05231 (Residues: 28-212; Coverage: 100%)
Gene names: IFNB2, IL6
Sequence domains: Interleukin-6/G-CSF/MGF family
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND SIMULATED ANNEALING.
Expression system: Escherichia coli