› 2ila

X-ray diffraction
2.3Å resolution

STRUCTURE OF INTERLEUKIN 1ALPHA AT 2.7-ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb2ila/pdb
PDB entry 2ila coloured by chain, front view.
PDB entry 2ila coloured by chain, side view.
PDB entry 2ila coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of interleukin 1 alpha at 2.7-A resolution.
Graves BJ, Hatada MH, Hendrickson WA, Miller JK, Madison VS, Satow Y
Biochemistry 29 2679-84 (1990)
PMID: 2346741

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134407 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-1 alpha Chain: A
Molecule details ›
Chain: A
Length: 155 amino acids
Theoretical weight: 17.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01583 (Residues: 117-271; Coverage: 57%)
Gene names: IL1A, IL1F1
Sequence domains: Interleukin-1 / 18

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 31.97Å b: 54.52Å c: 45.63Å
α: 90° β: 108.63° γ: 90°
R-values:
R R work R free
0.19 0.19 not available
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist.
Dinarello CA. (1998)
18 more

7 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
6 more