Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
- Beta-adaptin appendage, C-terminal subdomain
- Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
- Coatomer/calthrin adaptor appendage, C-terminal subdomain
- TBP domain superfamily
- AP complex subunit beta
- Clathrin adaptor, appendage, Ig-like subdomain superfamily
- Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Beta-arrestin-1 and AP-2 complex subunit beta (preferred)
PDBe Complex ID:
PDB-CPX-155942 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
AP-2 complex subunit beta
Molecule details ›
Chain: A
Length: 238 amino acids
Theoretical weight: 26.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Structure domains:
Length: 238 amino acids
Theoretical weight: 26.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P63010 (Residues: 700-937; Coverage: 25%)
Sequence domains:
Structure domains:
Beta-arrestin-1
Molecule details ›
Chains: P, Q
Length: 20 amino acids
Theoretical weight: 2.42 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 20 amino acids
Theoretical weight: 2.42 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P49407 (Residues: 383-402; Coverage: 5%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-1
Spacegroup:
P212121
Expression systems:
- Escherichia coli BL21
- Not provided
