› 2j1l

X-ray diffraction
2.5Å resolution

Crystal Structure of Human Rho-related GTP-binding protein RhoD

Released:
DOI: 10.2210/pdb2j1l/pdb
PDB entry 2j1l coloured by chain, front view.
PDB entry 2j1l coloured by chain, side view.
PDB entry 2j1l coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Pike ACW, Johansson C, Gileadi C, Niesen FH, Sobott F, Schoch G, Elkins J, Smee C, Gorrec F, Watt S, Bray J, Turnbull AP, von Delft F, Arrowsmith C, Edwards A, Weigelt J, Sundstrom M, Doyle D

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126154 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho-related GTP-binding protein RhoD Chain: A
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 24.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00212 (Residues: 7-197; Coverage: 91%)
Gene names: ARHD, RHOD
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand GDP 1 x GDP
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P3121
Unit cell:
a: 66.811Å b: 66.81Å c: 103.921Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.219 0.217 0.242
Expression system: Escherichia coli BL21(DE3)

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