Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151986 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha-5, N-terminally processed
Molecule details ›
Chains: A, B
Length: 450 amino acids
Theoretical weight: 49.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 450 amino acids
Theoretical weight: 49.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P52294 (Residues: 66-512; Coverage: 83%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Polymerase basic protein 2
Molecule details ›
Chains: D, E
Length: 83 amino acids
Theoretical weight: 8.99 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Influenza RNA polymerase PB2 C-terminal domain
Structure domains: Polymerase Basic Protein 2, C-terminal domain
Length: 83 amino acids
Theoretical weight: 8.99 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P31345 (Residues: 678-759; Coverage: 11%)
Sequence domains: Influenza RNA polymerase PB2 C-terminal domain
Structure domains: Polymerase Basic Protein 2, C-terminal domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-1
Spacegroup:
P212121
Expression systems:
- Escherichia coli BL21(DE3)
- Escherichia coli BL21
