Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148394 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Pituitary adenylate cyclase-activating polypeptide type I receptor
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 11.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Hormone receptor domain
Structure domains: GPCR, family 2, extracellular hormone receptor domain
Length: 106 amino acids
Theoretical weight: 11.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P41586 (Residues: 22-143; Coverage: 23%)
Sequence domains: Hormone receptor domain
Structure domains: GPCR, family 2, extracellular hormone receptor domain
Pituitary adenylate cyclase-activating polypeptide 38
Molecule details ›
Chain: B
Length: 33 amino acids
Theoretical weight: 4.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Peptide hormone
Length: 33 amino acids
Theoretical weight: 4.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P18509 (Residues: 137-169; Coverage: 22%)
Sequence domains: Peptide hormone
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
52%
Refinement method:
simulated annealing
Expression system: Escherichia coli
