› 2jtx

Solution NMR

NMR structure of the TFIIE-alpha carboxyl terminus

Released:
DOI: 10.2210/pdb2jtx/pdb
PDB entry 2jtx coloured by chain, ensemble of 20 models, front view.
PDB entry 2jtx coloured by chain, ensemble of 20 models, side view.
PDB entry 2jtx coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
p53 and TFIIEalpha share a common binding site on the Tfb1/p62 subunit of TFIIH.
Di Lello P, Miller Jenkins LM, Mas C, Langlois C, Malitskaya E, Fradet-Turcotte A, Archambault J, Legault P, Omichinski JG
Proc Natl Acad Sci U S A 105 106-11 (2008)
PMID: 18160537

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151350 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General transcription factor IIE subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 11.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29083 (Residues: 336-439; Coverage: 24%)
Gene names: GTF2E1, TF2E1
Sequence domains: C-terminal general transcription factor TFIIE alpha
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Posttranslational modification of p53: cooperative integrators of function.
Meek et al. (2009)
6 more

3 mentions without citation

p53 and TFIIEalpha share a common binding site on the Tfb1/p62 subunit of TFIIH.
Di Lello et al. (2008)
2 more