› 2jvx

Solution NMR

Solution Structure of human NEMO zinc finger

Released:
DOI: 10.2210/pdb2jvx/pdb
PDB entry 2jvx coloured by chain, ensemble of 10 models, front view.
PDB entry 2jvx coloured by chain, ensemble of 10 models, side view.
PDB entry 2jvx coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation.
Cordier F, Vinolo E, Véron M, Delepierre M, Agou F
J Mol Biol 377 1419-32 (2008)
PMID: 18313693

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195371 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NF-kappa-B essential modulator Chain: A
Molecule details ›
Chain: A
Length: 28 amino acids
Theoretical weight: 3.24 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9Y6K9 (Residues: 394-419; Coverage: 6%)
Gene names: FIP3, IKBKG, NEMO
Sequence domains: C2H2 type zinc-finger

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 47%
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

5 review citations

Molecular basis of NF-κB signaling.
Napetschnig et al. (2013)
4 more

16 mentions without citation

NF-κB regulation: lessons from structures.
Ghosh et al. (2012)
15 more