› 2jwe

Solution NMR

Solution structure of the second PDZ domain from human zonula occludens-1: A dimeric form with 3D domain swapping

Released:
DOI: 10.2210/pdb2jwe/pdb
PDB entry 2jwe coloured by chain, ensemble of 20 models, front view.
PDB entry 2jwe coloured by chain, ensemble of 20 models, side view.
PDB entry 2jwe coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the second PDZ domain of Zonula Occludens 1.
Ji P, Yang G, Zhang J, Wu J, Chen Z, Gong Q, Wu J, Shi Y
Proteins 79 1342-6 (2011)
PMID: 21387411

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170449 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tight junction protein ZO-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 88 amino acids
Theoretical weight: 10.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07157 (Residues: 185-264; Coverage: 5%)
Gene names: TJP1, ZO1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structural Features of Tight-Junction Proteins.
Heinemann et al. (2019)
1 other article

1 mention without citation

Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.
Zhu et al. (2022)