› 2jxw

Solution NMR

Solution Structure of the Tandem WW Domains of FBP21

Released:
DOI: 10.2210/pdb2jxw/pdb
PDB entry 2jxw coloured by chain, ensemble of 20 models, front view.
PDB entry 2jxw coloured by chain, ensemble of 20 models, side view.
PDB entry 2jxw coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21).
Huang X, Beullens M, Zhang J, Zhou Y, Nicolaescu E, Lesage B, Hu Q, Wu J, Bollen M, Shi Y
J Biol Chem 284 25375-87 (2009)
PMID: 19592703

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131052 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
WW domain-binding protein 4 Chain: A
Molecule details ›
Chain: A
Length: 75 amino acids
Theoretical weight: 8.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75554 (Residues: 122-196; Coverage: 20%)
Gene names: FBP21, FNBP21, WBP4
Sequence domains: WW domain
Structure domains: Ubiquitin Ligase Nedd4; Chain: W;

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 79%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

21 citation in other articles

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Bertram et al. (2017)
20 more

13 mentions without citation

Versatile communication strategies among tandem WW domain repeats.
Dodson et al. (2015)
12 more