› 2jzi

Solution NMR

Structure of Calmodulin complexed with the Calmodulin Binding Domain of Calcineurin

Released:
DOI: 10.2210/pdb2jzi/pdb
PDB entry 2jzi coloured by chain, ensemble of 20 models, front view.
PDB entry 2jzi coloured by chain, ensemble of 20 models, side view.
PDB entry 2jzi coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Chyan C, Huang J, Irene D, Lin T

Function and Biology Details

Reaction catalysed: 
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143944 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP23 (Residues: 2-149; Coverage: 99%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
Protein phosphatase 3 catalytic subunit alpha Chain: B
Molecule details ›
Chain: B
Length: 24 amino acids
Theoretical weight: 2.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08209 (Residues: 391-414; Coverage: 5%)
Gene names: CALNA, CNA, PPP3CA

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry
Expression system: Escherichia coli

Quick links