› 2k1j

Solution NMR

Plan homeodomain finger of tumour supressor ING4

Released:
DOI: 10.2210/pdb2k1j/pdb
PDB entry 2k1j coloured by chain, ensemble of 25 models, front view.
PDB entry 2k1j coloured by chain, ensemble of 25 models, side view.
PDB entry 2k1j coloured by chain, ensemble of 25 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and NMR characterization of the binding to methylated histone tails of the plant homeodomain finger of the tumour suppressor ING4.
Palacios A, Garcia P, Padró D, López-Hernández E, Martín I, Blanco FJ
FEBS Lett 580 6903-8 (2006)
PMID: 17157298

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inhibitor of growth protein 4 Chain: A
Molecule details ›
Chain: A
Length: 63 amino acids
Theoretical weight: 7.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9UNL4 (Residues: 187-249; Coverage: 25%)
Gene names: ING4, My036
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21

Quick links

Citations

8 review citations

Aire.
Mathis et al. (2009)
7 more

3 mentions without citation

Structural insight into histone recognition by the ING PHD fingers.
Champagne et al. (2009)
2 more