› 2k20

Solution NMR

Solution structure of Par-3 PDZ3 in complex with PTEN peptide

Released:
DOI: 10.2210/pdb2k20/pdb
PDB entry 2k20 coloured by chain, ensemble of 20 models, front view.
PDB entry 2k20 coloured by chain, ensemble of 20 models, side view.
PDB entry 2k20 coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus norvegicus
Entry authors: Feng W, Wu H, Chan L, Zhang M

Function and Biology Details

Reactions catalysed: 
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Phosphatidylinositol 3,4,5-trisphosphate + H(2)O = phosphatidylinositol 4,5-bisphosphate + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129513 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Partitioning defective 3 homolog Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 11.14 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Z340 (Residues: 582-685; Coverage: 8%)
Gene names: Par3, Pard3
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Chain: B
Molecule details ›
Chain: B
Length: 11 amino acids
Theoretical weight: 1.3 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O54857 (Residues: 393-403; Coverage: 3%)
Gene names: Pten, rCG_47874

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

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